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Structural Rigidity and Protein Thermostability in Variants of Lipase A from Bacillus subtilis

Understanding the origin of thermostability is of fundamental importance in protein biochemistry. Opposing views on increased or decreased structural rigidity of the folded state have been put forward in this context. They have been related to differences in the temporal resolution of experiments an...

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Publicat a:PLoS One
Autors principals: Rathi, Prakash Chandra, Jaeger, Karl-Erich, Gohlke, Holger
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493141/
https://ncbi.nlm.nih.gov/pubmed/26147762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130289
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