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COX-2 modulates mammary tumor progression in response to collagen density

BACKGROUND: High breast density is linked to an increased risk of breast cancer, and correlates with changes in collagen. In a mouse model of mammary carcinoma in the context of increased collagen deposition, the MMTV-PyMT/Col1a1(tm1jae), there is accelerated mammary tumor formation and progression....

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Bibliografische gegevens
Gepubliceerd in:Breast Cancer Res
Hoofdauteurs: Esbona, Karla, Inman, David, Saha, Sandeep, Jeffery, Justin, Schedin, Pepper, Wilke, Lee, Keely, Patricia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802888/
https://ncbi.nlm.nih.gov/pubmed/27000374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0695-3
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