COX-2 modulates mammary tumor progression in response to collagen density

BACKGROUND: High breast density is linked to an increased risk of breast cancer, and correlates with changes in collagen. In a mouse model of mammary carcinoma in the context of increased collagen deposition, the MMTV-PyMT/Col1a1(tm1jae), there is accelerated mammary tumor formation and progression....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Breast Cancer Res
Main Authors: Esbona, Karla, Inman, David, Saha, Sandeep, Jeffery, Justin, Schedin, Pepper, Wilke, Lee, Keely, Patricia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802888/
https://ncbi.nlm.nih.gov/pubmed/27000374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0695-3
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