N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis

In recent history, alternative approaches to Edman sequencing have been investigated, and to this end, the Association of Biomolecular Resource Facilities (ABRF) Protein Sequencing Research Group (PSRG) initiated studies in 2014 and 2015, looking into bottom-up and top-down N-terminal (Nt) dimethyl...

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Détails bibliographiques
Publié dans:J Biomol Tech
Auteurs principaux: Chang, Elizabeth, Pourmal, Sergei, Zhou, Chun, Kumar, Rupesh, Teplova, Marianna, Pavletich, Nikola P., Marians, Kenneth J., Erdjument-Bromage, Hediye
Format: Artigo
Langue:Inglês
Publié: Association of Biomolecular Resource Facilities 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802820/
https://ncbi.nlm.nih.gov/pubmed/27006647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7171/jbt.16-2702-002
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