N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis

In recent history, alternative approaches to Edman sequencing have been investigated, and to this end, the Association of Biomolecular Resource Facilities (ABRF) Protein Sequencing Research Group (PSRG) initiated studies in 2014 and 2015, looking into bottom-up and top-down N-terminal (Nt) dimethyl...

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Publicado en:J Biomol Tech
Autores principales: Chang, Elizabeth, Pourmal, Sergei, Zhou, Chun, Kumar, Rupesh, Teplova, Marianna, Pavletich, Nikola P., Marians, Kenneth J., Erdjument-Bromage, Hediye
Formato: Artigo
Lenguaje:Inglês
Publicado: Association of Biomolecular Resource Facilities 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802820/
https://ncbi.nlm.nih.gov/pubmed/27006647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7171/jbt.16-2702-002
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