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Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of end-stage renal disease. The molecular pathogenesis of ADPKD is not completely known and there is no approved therapy. To date, there is limited knowledge concerning the molecular consequences of specific dise...
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| Gepubliceerd in: | Kidney Int |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801696/ https://ncbi.nlm.nih.gov/pubmed/26924047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2015.11.015 |
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