Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment

Oncolytic virotherapy is an emergent promising therapeutic approach for the treatment of cancer. We have constructed a vaccinia virus (WR strain) deleted for thymidine kinase (TK) and ribonucleotide reductase (RR) genes that expressed the fusion suicide gene FCU1 derived from the yeast cytosine deam...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Fend, Laetitia, Remy-Ziller, Christelle, Foloppe, Johann, Kempf, Juliette, Cochin, Sandrine, Barraud, Luc, Accart, Nathalie, Erbs, Philippe, Fournel, Sylvie, Préville, Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801465/
https://ncbi.nlm.nih.gov/pubmed/27057460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1080414
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