Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist

Eitemau Tebyg

• Shaping the tumor microenvironment with Modified Vaccinia Virus Ankara and TLR9 ligand
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  Cyhoeddwyd: (2015)
• Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment
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  Cyhoeddwyd: (2015)
• Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition
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  Cyhoeddwyd: (2016)
• TLR2 ligation protects effector T cells from regulatory T-cell mediated suppression and repolarizes T helper responses following MVA-based cancer immunotherapy
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  Cyhoeddwyd: (2012)
• Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory
  gan: Hinterberger, Maria, et al.
  Cyhoeddwyd: (2021)