Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment

Oncolytic virotherapy is an emergent promising therapeutic approach for the treatment of cancer. We have constructed a vaccinia virus (WR strain) deleted for thymidine kinase (TK) and ribonucleotide reductase (RR) genes that expressed the fusion suicide gene FCU1 derived from the yeast cytosine deam...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Fend, Laetitia, Remy-Ziller, Christelle, Foloppe, Johann, Kempf, Juliette, Cochin, Sandrine, Barraud, Luc, Accart, Nathalie, Erbs, Philippe, Fournel, Sylvie, Préville, Xavier
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801465/
https://ncbi.nlm.nih.gov/pubmed/27057460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1080414
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