Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment

Oncolytic virotherapy is an emergent promising therapeutic approach for the treatment of cancer. We have constructed a vaccinia virus (WR strain) deleted for thymidine kinase (TK) and ribonucleotide reductase (RR) genes that expressed the fusion suicide gene FCU1 derived from the yeast cytosine deam...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Fend, Laetitia, Remy-Ziller, Christelle, Foloppe, Johann, Kempf, Juliette, Cochin, Sandrine, Barraud, Luc, Accart, Nathalie, Erbs, Philippe, Fournel, Sylvie, Préville, Xavier
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801465/
https://ncbi.nlm.nih.gov/pubmed/27057460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1080414
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