Vaccine-induced but not tumor-derived Interleukin-10 dictates the efficacy of Interleukin-10 blockade in therapeutic vaccination

Blocking antibodies against immunosuppressive molecules have shown promising results in cancer patients. However, there are not enough data to define those conditions dictating treatment efficacy. In this scenario, IL-10 is a cytokine with controversial effects on tumor growth. Thus, our aim was to...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Llopiz, Diana, Aranda, Fernando, Díaz-Valdés, Nancy, Ruiz, Marta, Infante, Stefany, Belsúe, Virginia, Lasarte, Juan José, Sarobe, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801433/
https://ncbi.nlm.nih.gov/pubmed/27057445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1075113
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