Vaccine-induced but not tumor-derived Interleukin-10 dictates the efficacy of Interleukin-10 blockade in therapeutic vaccination

Blocking antibodies against immunosuppressive molecules have shown promising results in cancer patients. However, there are not enough data to define those conditions dictating treatment efficacy. In this scenario, IL-10 is a cytokine with controversial effects on tumor growth. Thus, our aim was to...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Llopiz, Diana, Aranda, Fernando, Díaz-Valdés, Nancy, Ruiz, Marta, Infante, Stefany, Belsúe, Virginia, Lasarte, Juan José, Sarobe, Pablo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801433/
https://ncbi.nlm.nih.gov/pubmed/27057445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1075113
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