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Single-cell analysis of transcription kinetics across the cell cycle

Transcription is a highly stochastic process. To infer transcription kinetics for a gene-of-interest, researchers commonly compare the distribution of mRNA copy-number to the prediction of a theoretical model. However, the reliability of this procedure is limited because the measured mRNA numbers re...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Skinner, Samuel O, Xu, Heng, Nagarkar-Jaiswal, Sonal, Freire, Pablo R, Zwaka, Thomas P, Golding, Ido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801054/
https://ncbi.nlm.nih.gov/pubmed/26824388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12175
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