Effects of an amyloid-beta 1-42 oligomers antibody screened from a phage display library in APP/PS1 transgenic mice

We screened anti-Aβ1-42 antibodies from a human Alzheimer’s disease (AD) specific single chain variable fragment (scFv) phage display library and assessed their effects in APP/PS1 transgenic mice. Reverse transcription-PCR was used to construct the scFv phage display library, and screening identifie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Res
Prif Awduron: Wang, Jianping, Li, Nan, Ma, Jun, Gu, Zhiqiang, Yu, Lie, Fu, Xiaojie, Liu, Xi, Wang, Jian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801032/
https://ncbi.nlm.nih.gov/pubmed/26820640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.01.028
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg