Effects of an amyloid-beta 1-42 oligomers antibody screened from a phage display library in APP/PS1 transgenic mice

We screened anti-Aβ1-42 antibodies from a human Alzheimer’s disease (AD) specific single chain variable fragment (scFv) phage display library and assessed their effects in APP/PS1 transgenic mice. Reverse transcription-PCR was used to construct the scFv phage display library, and screening identifie...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Wang, Jianping, Li, Nan, Ma, Jun, Gu, Zhiqiang, Yu, Lie, Fu, Xiaojie, Liu, Xi, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801032/
https://ncbi.nlm.nih.gov/pubmed/26820640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.01.028
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