Memantine Lowers Amyloid-beta Peptide Levels in Neuronal Cultures and in APP/PS1 Transgenic Mice

Memantine is a moderate-affinity, uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that stabilizes cognitive, functional, and behavioral decline in patients with moderate to severe Alzheimer’s disease (AD). In AD, the extracellular deposition of fibrillogenic amyloid-beta peptides (Aβ)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Alley, George M., Bailey, Jason A, Chen, DeMao, Ray, Balmiki, Puli, Lakshman K., Tanila, Heikki, Banerjee, Pradeep K, Lahiri, Debomoy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783840/
https://ncbi.nlm.nih.gov/pubmed/19642202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22172
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados