A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children

AIMS: Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this study were to characterize the population pharmacokinetics (popPK) of rifampicin in Malawian children and adults with tuberculosis, simulate e...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K., van Oosterhout, Joep J., Ward, Steve A., Khoo, Saye, Davies, Gerry
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799933/
https://ncbi.nlm.nih.gov/pubmed/26613187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12848
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