A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children

AIMS: Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this study were to characterize the population pharmacokinetics (popPK) of rifampicin in Malawian children and adults with tuberculosis, simulate e...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K., van Oosterhout, Joep J., Ward, Steve A., Khoo, Saye, Davies, Gerry
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799933/
https://ncbi.nlm.nih.gov/pubmed/26613187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12848
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