A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children

AIMS: Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this study were to characterize the population pharmacokinetics (popPK) of rifampicin in Malawian children and adults with tuberculosis, simulate e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Clin Pharmacol
Main Authors: Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K., van Oosterhout, Joep J., Ward, Steve A., Khoo, Saye, Davies, Gerry
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799933/
https://ncbi.nlm.nih.gov/pubmed/26613187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12848
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