A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children

AIMS: Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this study were to characterize the population pharmacokinetics (popPK) of rifampicin in Malawian children and adults with tuberculosis, simulate e...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K., van Oosterhout, Joep J., Ward, Steve A., Khoo, Saye, Davies, Gerry
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799933/
https://ncbi.nlm.nih.gov/pubmed/26613187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12848
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