Small molecule mediated inhibition of ROR γ‐dependent gene expression and autoimmune disease pathology in vivo

Retinoic acid receptor‐related orphan nuclear receptor γ (ROR γ) orchestrates a pro‐inflammatory gene expression programme in multiple lymphocyte lineages including T helper type 17 (Th17) cells, γδ T cells, innate lymphoid cells and lymphoid tissue inducer cells. There is compelling evidence that R...

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Bibliographic Details
Published in:Immunology
Main Authors: Banerjee, Daliya, Zhao, Linlin, Wu, Lan, Palanichamy, Arumugam, Ergun, Ayla, Peng, Liaomin, Quigley, Catherine, Hamann, Stefan, Dunstan, Robert, Cullen, Patrick, Allaire, Norm, Guertin, Kevin, Wang, Tao, Chao, Jianhua, Loh, Christine, Fontenot, Jason D.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799885/
https://ncbi.nlm.nih.gov/pubmed/26694902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12570
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