RORγt, but not T-bet, Overexpression Exacerbates an Autoimmune Model for Multiple Sclerosis

Th17 cells play an important role in multiple sclerosis (MS) and its autoimmune model, experimental autoimmune encephalomyelitis (EAE). However, studies have not addressed how enhanced Th17 immune responses can affect demyelinating diseases. We induced EAE with MOG in RORγt transgenic C57BL/6 mice t...

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Detalhes bibliográficos
Publicado no:J Neuroimmunol
Main Authors: Martinez, Nicholas E., Sato, Fumitaka, Omura, Seiichi, Kawai, Eiichiro, Takahashi, Satoru, Yoh, Keigyou, Tsunoda, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252371/
https://ncbi.nlm.nih.gov/pubmed/25288300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.09.006
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