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Endosomal Proteolysis of the Ebola Virus Glycoprotein Is Necessary for Infection

Ebola virus (EboV) causes rapidly fatal hemorrhagic fever in humans and there is currently no effective treatment. We found that the infection of African green monkey kidney (Vero) cells by vesicular stomatitis viruses bearing the EboV glycoprotein (GP) requires the activity of endosomal cysteine pr...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Chandran, Kartik, Sullivan, Nancy J., Felbor, Ute, Whelan, Sean P., Cunningham, James M.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797943/
https://ncbi.nlm.nih.gov/pubmed/15831716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1110656
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