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Proteolysis of the Ebola Virus Glycoproteins Enhances Virus Binding and Infectivity

Cellular cathepsins are required for Ebola virus infection and are believed to proteolytically process the Ebola virus glycoprotein (GP) during entry. However, the significance of cathepsin cleavage during infection remains unclear. Here we demonstrate a role for cathepsin L (CatL) cleavage of Ebola...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kaletsky, Rachel L., Simmons, Graham, Bates, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168880/
https://ncbi.nlm.nih.gov/pubmed/17928356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01170-07
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