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Proteolysis of the Ebola Virus Glycoproteins Enhances Virus Binding and Infectivity

Cellular cathepsins are required for Ebola virus infection and are believed to proteolytically process the Ebola virus glycoprotein (GP) during entry. However, the significance of cathepsin cleavage during infection remains unclear. Here we demonstrate a role for cathepsin L (CatL) cleavage of Ebola...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kaletsky, Rachel L., Simmons, Graham, Bates, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168880/
https://ncbi.nlm.nih.gov/pubmed/17928356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01170-07
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