Inhibition of Ebola Virus Entry by a C-peptide Targeted to Endosomes

Ebola virus (EboV) and Marburg virus (MarV) (filoviruses) are the causative agents of severe hemorrhagic fever. Infection begins with uptake of particles into cellular endosomes, where the viral envelope glycoprotein (GP) catalyzes fusion between the viral and host cell membranes. This fusion event...

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Main Authors: Miller, Emily Happy, Harrison, Joseph S., Radoshitzky, Sheli R., Higgins, Chelsea D., Chi, Xiaoli, Dong, Lian, Kuhn, Jens H., Bavari, Sina, Lai, Jonathan R., Chandran, Kartik
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091195/
https://ncbi.nlm.nih.gov/pubmed/21454542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207084
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