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An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells

Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved. We designed an immunotoxin in which a single-chain...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Cai, Yingyun, Yu, Shuiqing, Chi, Xiaoli, Radoshitzky, Sheli R., Kuhn, Jens H., Berger, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790382/
https://ncbi.nlm.nih.gov/pubmed/33411835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245024
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