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Rereplication by Depletion of Geminin Is Seen Regardless of p53 Status and Activates a G(2)/M Checkpoint
Genomic DNA replication is tightly controlled to ensure that DNA replication occurs once per cell cycle; loss of this control leads to genomic instability. Geminin, a DNA replication inhibitor, plays an important role in regulation of DNA replication. To investigate the role of human geminin in the...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC479725/ https://ncbi.nlm.nih.gov/pubmed/15282313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7140-7150.2004 |
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