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Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression

Increasing evidence shows that hyperoxia is a serious complication of oxygen therapy in acutely ill patients that causes excessive production of free radicals leading to hyperoxia-induced acute lung injury (HALI). Our previous studies have shown that P2X7 receptor activation is required for inflamma...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Galam, Lakshmi, Rajan, Ashna, Failla, Athena, Soundararajan, Ramani, Lockey, Richard F., Kolliputi, Narasaiah
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796258/
https://ncbi.nlm.nih.gov/pubmed/26747786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00417.2015
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