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Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression

Increasing evidence shows that hyperoxia is a serious complication of oxygen therapy in acutely ill patients that causes excessive production of free radicals leading to hyperoxia-induced acute lung injury (HALI). Our previous studies have shown that P2X7 receptor activation is required for inflamma...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Physiol Lung Cell Mol Physiol
Main Authors: Galam, Lakshmi, Rajan, Ashna, Failla, Athena, Soundararajan, Ramani, Lockey, Richard F., Kolliputi, Narasaiah
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796258/
https://ncbi.nlm.nih.gov/pubmed/26747786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00417.2015
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