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4-Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells

Prolonged exposure to oxidative stress causes Acute Lung Injury (ALI) and significantly impairs pulmonary function. Previously we have demonstrated that mitochondrial dysfunction is a key pathological factor in hyperoxic ALI. While it is known that hyperoxia induces the production of stable, but tox...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Galam, Lakshmi, Failla, Athena, Soundararajan, Ramani, Lockey, Richard F., Kolliputi, Narasaiah
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747170/
https://ncbi.nlm.nih.gov/pubmed/26484418
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