4-Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells

Prolonged exposure to oxidative stress causes Acute Lung Injury (ALI) and significantly impairs pulmonary function. Previously we have demonstrated that mitochondrial dysfunction is a key pathological factor in hyperoxic ALI. While it is known that hyperoxia induces the production of stable, but tox...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Galam, Lakshmi, Failla, Athena, Soundararajan, Ramani, Lockey, Richard F., Kolliputi, Narasaiah
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper: Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747170/
https://ncbi.nlm.nih.gov/pubmed/26484418
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