4-Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells

Prolonged exposure to oxidative stress causes Acute Lung Injury (ALI) and significantly impairs pulmonary function. Previously we have demonstrated that mitochondrial dysfunction is a key pathological factor in hyperoxic ALI. While it is known that hyperoxia induces the production of stable, but tox...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Galam, Lakshmi, Failla, Athena, Soundararajan, Ramani, Lockey, Richard F., Kolliputi, Narasaiah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper: Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747170/
https://ncbi.nlm.nih.gov/pubmed/26484418
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