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Mitochondrial protein hyperacetylation in the failing heart

Myocardial fuel and energy metabolic derangements contribute to the pathogenesis of heart failure. Recent evidence implicates posttranslational mechanisms in the energy metabolic disturbances that contribute to the pathogenesis of heart failure. We hypothesized that accumulation of metabolite interm...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Horton, Julie L., Martin, Ola J., Lai, Ling, Riley, Nicholas M., Richards, Alicia L., Vega, Rick B., Leone, Teresa C., Pagliarini, David J., Muoio, Deborah M., Bedi, Kenneth C., Margulies, Kenneth B., Coon, Joshua J., Kelly, Daniel P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795836/
https://ncbi.nlm.nih.gov/pubmed/26998524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.84897
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