Mitochondrial protein hyperacetylation in the failing heart

Myocardial fuel and energy metabolic derangements contribute to the pathogenesis of heart failure. Recent evidence implicates posttranslational mechanisms in the energy metabolic disturbances that contribute to the pathogenesis of heart failure. We hypothesized that accumulation of metabolite interm...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Horton, Julie L., Martin, Ola J., Lai, Ling, Riley, Nicholas M., Richards, Alicia L., Vega, Rick B., Leone, Teresa C., Pagliarini, David J., Muoio, Deborah M., Bedi, Kenneth C., Margulies, Kenneth B., Coon, Joshua J., Kelly, Daniel P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795836/
https://ncbi.nlm.nih.gov/pubmed/26998524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.84897
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