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Energy Metabolic Re-Programming in the Hypertrophied and Early Stage Failing Heart: A Multi-systems Approach

BACKGROUND: An unbiased systems approach was utilized to define energy metabolic events that occur during the pathologic cardiac remodeling en route to heart failure. METHODS AND RESULTS: Combined myocardial transcriptomic and metabolomic profiling were conducted in a well-defined mouse model of hea...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Lai, Ling, Leone, Teresa C., Keller, Mark P., Martin, Ola J., Broman, Aimee T., Nigro, Jessica, Kapoor, Kapil, Koves, Timothy R., Stevens, Robert, Ilkayeva, Olga R., Vega, Rick B., Attie, Alan D., Muoio, Deborah M., Kelly, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241130/
https://ncbi.nlm.nih.gov/pubmed/25236884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001469
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