Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells

Tocopherylquinone (TQ), the oxidation product of alpha-tocopherol (AT), is a bioactive molecule with distinct properties from AT. In this study, AT and TQ are investigated for their comparative effects on growth and androgenic activity in prostate cancer cells. TQ potently inhibited the growth of an...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Fajardo, Alexandra M., MacKenzie, Debra A., Olguin, Sarah L., Scariano, John K., Rabinowitz, Ian, Thompson, Todd A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795544/
https://ncbi.nlm.nih.gov/pubmed/26986969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151525
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