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Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells

Tocopherylquinone (TQ), the oxidation product of alpha-tocopherol (AT), is a bioactive molecule with distinct properties from AT. In this study, AT and TQ are investigated for their comparative effects on growth and androgenic activity in prostate cancer cells. TQ potently inhibited the growth of an...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Fajardo, Alexandra M., MacKenzie, Debra A., Olguin, Sarah L., Scariano, John K., Rabinowitz, Ian, Thompson, Todd A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795544/
https://ncbi.nlm.nih.gov/pubmed/26986969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151525
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