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The Curcumin Analog ca27 Down-Regulates Androgen Receptor Through an Oxidative Stress Mediated Mechanism in Human Prostate Cancer Cells

BACKGROUND: The androgen receptor (AR) plays a critical role in prostate cancer development and progression. Therefore, the inhibition of AR function is an established therapeutic intervention. Since the expression of the AR is retained and often increased in progressive disease, AR protein down-reg...

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Detalhes bibliográficos
Main Authors: Fajardo, Alexandra M., MacKenzie, Debra A., Ji, Ming, Deck, Lorraine M., Vander Jagt, David L., Thompson, Todd A., Bisoffi, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309160/
https://ncbi.nlm.nih.gov/pubmed/21796654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21464
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