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Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator
BACKGROUND: Urokinase-type plasminogen activator (uPA) plays a major role in extracellular proteolytic events associated with tumor cell growth, migration and angiogenesis. Consequently, uPA is an attractive target for the development of small molecule active site inhibitors. Most of the recent drug...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479381/ https://ncbi.nlm.nih.gov/pubmed/16466576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-6-1 |
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