Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator

BACKGROUND: Urokinase-type plasminogen activator (uPA) plays a major role in extracellular proteolytic events associated with tumor cell growth, migration and angiogenesis. Consequently, uPA is an attractive target for the development of small molecule active site inhibitors. Most of the recent drug...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Heynekamp, Justin J, Hunsaker, Lucy A, Vander Jagt, Thomas A, Deck, Lorraine M, Vander Jagt, David L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479381/
https://ncbi.nlm.nih.gov/pubmed/16466576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-6-1
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi