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Isocoumarin-based Inhibitors of Pancreatic Cholesterol Esterase

Pancreatic cholesterol esterase (CEase), which is secreted from the exocrine pancreas, is a serine hydrolase that aids in the bile salt-dependent hydrolysis of dietary cholesteryl esters and contributes to the hydrolysis of triglycerides and phospholipids. Additional roles for CEase in intestinal mi...

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Autores principales: Heynekamp, Justin J., Hunsaker, Lucy A., Vander Jagt, Thomas A., Royer, Robert E., Deck, Lorraine M., Vander Jagt, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474762/
https://ncbi.nlm.nih.gov/pubmed/18353652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.03.016
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