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PGC-1alpha Down-Regulation Affects the Antioxidant Response in Friedreich's Ataxia
BACKGROUND: Cells from individuals with Friedreich's ataxia (FRDA) show reduced activities of antioxidant enzymes and cannot up-regulate their expression when exposed to oxidative stress. This blunted antioxidant response may play a central role in the pathogenesis. We previously reported that...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850922/ https://ncbi.nlm.nih.gov/pubmed/20383327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010025 |
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