High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding.
We have isolated RNA ligands with low-nanomolar affinity and high specificity to basic fibroblast growth factor from a pool of 10(14) molecules containing 30 randomized positions by the systematic evolution of ligands by exponential enrichment (SELEX) procedure. High-affinity ligands could be classi...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1993
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11227 |
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