High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding.

We have isolated RNA ligands with low-nanomolar affinity and high specificity to basic fibroblast growth factor from a pool of 10(14) molecules containing 30 randomized positions by the systematic evolution of ligands by exponential enrichment (SELEX) procedure. High-affinity ligands could be classi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Jellinek, D, Lynott, C K, Rifkin, D B, Janjić, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47955/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11227
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