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High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding.

We have isolated RNA ligands with low-nanomolar affinity and high specificity to basic fibroblast growth factor from a pool of 10(14) molecules containing 30 randomized positions by the systematic evolution of ligands by exponential enrichment (SELEX) procedure. High-affinity ligands could be classi...

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Detalhes bibliográficos
Main Authors: Jellinek, D, Lynott, C K, Rifkin, D B, Janjić, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47955/
https://ncbi.nlm.nih.gov/pubmed/7504300
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