Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines.

We demonstrate that transfer of a yeast artificial chromosome (YAC) containing 230 kb of the human beta-globin locus into mouse erythroleukemia cells by fusion results in correct developmental regulation of the human beta-like globin genes. Additionally, we show that early after hybrid formation, hu...

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Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Peterson, K R, Zitnik, G, Huxley, C, Lowrey, C H, Gnirke, A, Leppig, K A, Papayannopoulou, T, Stamatoyannopoulos, G
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1993
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11207
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