Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines.

We demonstrate that transfer of a yeast artificial chromosome (YAC) containing 230 kb of the human beta-globin locus into mouse erythroleukemia cells by fusion results in correct developmental regulation of the human beta-like globin genes. Additionally, we show that early after hybrid formation, hu...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Peterson, K R, Zitnik, G, Huxley, C, Lowrey, C H, Gnirke, A, Leppig, K A, Papayannopoulou, T, Stamatoyannopoulos, G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC47951/
https://ncbi.nlm.nih.gov/pubmed/8248229
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky