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CNS accumulation of regulatory B cells is VLA-4-dependent
OBJECTIVE: To investigate the role of very late antigen-4 (VLA-4) on regulatory B cells (Breg) in CNS autoimmune disease. METHODS: Experimental autoimmune encephalomyelitis (EAE) was induced in mice selectively deficient for VLA-4 on B cells (CD19cre/α4(f/f)) by immunization with myelin oligodendroc...
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| izdano v: | Neurol Neuroimmunol Neuroinflamm |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Lippincott Williams & Wilkins
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794810/ https://ncbi.nlm.nih.gov/pubmed/27027096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000212 |
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