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Reduction of CD8(+) T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate

OBJECTIVE: To evaluate the influence of dimethyl fumarate (DMF, Tecfidera) treatment of multiple sclerosis (MS) on leukocyte and lymphocyte subsets. METHODS: Peripheral blood leukocyte and lymphocyte subsets, including CD3(+), CD4(+), and CD8(+) T cells; CD19(+) B cells; and CD56(+) natural killer (...

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Detalhes bibliográficos
Publicado no:Neurol Neuroimmunol Neuroinflamm
Main Authors: Spencer, Collin M., Crabtree-Hartman, Elizabeth C., Lehmann-Horn, Klaus, Cree, Bruce A.C., Zamvil, Scott S.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335821/
https://ncbi.nlm.nih.gov/pubmed/25738172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000076
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