A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal Antibodies

Hepatitis C virus (HCV) infection is a global health problem, with millions of chronically infected individuals at risk for cirrhosis and hepatocellular carcinoma. HCV vaccine development is vital in the effort toward disease control and eradication, an undertaking aided by an increased understandin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wasilewski, Lisa N., El-Diwany, Ramy, Munshaw, Supriya, Snider, Anna E., Brady, Jillian K., Osburn, William O., Ray, Stuart C., Bailey, Justin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794665/
https://ncbi.nlm.nih.gov/pubmed/26819308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02837-15
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