Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance

For hepatitis C virus (HCV) and other highly variable viruses, broadly neutralizing mAbs are an important guide for vaccine development. The development of resistance to anti-HCV mAbs is poorly understood, in part due to a lack of neutralization testing against diverse, representative panels of HCV...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bailey, Justin R., Wasilewski, Lisa N., Snider, Anna E., El-Diwany, Ramy, Osburn, William O., Keck, Zhenyong, Foung, Steven K.H., Ray, Stuart C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382262/
https://ncbi.nlm.nih.gov/pubmed/25500884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78794
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