Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA

The cell adhesion protein and tumour suppressor E-cadherin exhibits important functions in the prevention of gastric cancer. As a class-I carcinogen, Helicobacter pylori (H. pylori) has developed a unique strategy to interfere with E-cadherin functions. In previous studies, we have demonstrated that...

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Udgivet i:Sci Rep
Main Authors: Schmidt, Thomas P., Perna, Anna M., Fugmann, Tim, Böhm, Manja, Jan Hiss, Haller, Sarah, Götz, Camilla, Tegtmeyer, Nicole, Hoy, Benjamin, Rau, Tilman T., Neri, Dario, Backert, Steffen, Schneider, Gisbert, Wessler, Silja
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794652/
https://ncbi.nlm.nih.gov/pubmed/26983597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23264
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