Peptide lineup against Gram-negative bacterial infection – first-in-class peptide inhibitor of H. pylori HtrA

Eitemau Tebyg

• Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA
  gan: Schmidt, Thomas P., et al.
  Cyhoeddwyd: (2016)
• Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?
  gan: Wessler, Silja, et al.
  Cyhoeddwyd: (2017)
• Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion
  gan: Hoy, Benjamin, et al.
  Cyhoeddwyd: (2010)
• Fragment-Based De Novo Design Reveals a Small-Molecule Inhibitor of Helicobacter Pylori HtrA**
  gan: Perna, Anna M., et al.
  Cyhoeddwyd: (2015)
• Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA
  gan: Schmidt, Thomas P., et al.
  Cyhoeddwyd: (2016)