HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens

BACKGROUND: The serine proteases HtrA/DegP secreted by the human gastrointestinal pathogens Helicobacter pylori (H. pylori) and Campylobacter jejuni (C. jejuni) cleave the mammalian cell adhesion protein E-cadherin to open intercellular adhesions. A wide range of bacteria also expresses the HtrA/Deg...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Abfalter, Carmen M., Schubert, Maria, Götz, Camilla, Schmidt, Thomas P., Posselt, Gernot, Wessler, Silja
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146865/
https://ncbi.nlm.nih.gov/pubmed/27931258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0153-y
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